THE ABSORPTION PROBLEM
What you consume ≠ What your body uses.
Most vitamins and minerals in traditional supplements never make it past the gut. They’re broken down, filtered out, or excreted — long before reaching your cells.
This gap between intake and impact is called the bioavailability barrier.
DEFINING BIOAVAILABILITY
Bioavailability is the proportion of a nutrient that enters the circulation when introduced into the body and is able to have an active effect.
Key factors influencing bioavailability:
| Factor | Impact on Absorption |
|---|---|
| Solubility in water/fat | Determines uptake efficiency |
| Stability in GI tract | Prevents degradation |
| Molecular size and weight | Affects cellular permeability |
| Delivery system | Dictates transport and release |
THE LIMITATIONS OF TRADITIONAL SUPPLEMENTS
Clinical absorption data from standard oral supplements:
| Nutrient | Dose (mg) | Avg. Absorbed (mg) | Bioavailability |
|---|---|---|---|
| Vitamin C (tab) | 1000 | ~120–150 | ~12–15% |
| CoQ10 | 200 | ~12–15 | ~6–10% |
| Vitamin B12 | 500 | ~<5 | Often <1% |
These numbers reveal a significant gap between what’s on the label and what’s reaching your bloodstream.
THE LIPOSOMAL SOLUTION
Liposomal Encapsulation Technology enhances nutrient absorption by protecting nutrients inside lipid bilayer vesicles that mimic human cell membranes.
Mechanism of Action:
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Encapsulation: Nutrients are coated in phospholipids (similar to your own cells).
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Protection: Liposomes shield nutrients from stomach acid and enzymes.
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Absorption: Lipid layers facilitate fusion with intestinal membranes, delivering nutrients directly to cells.
DATA-DRIVEN ADVANTAGE: CLINICAL PROOF
Independent Human Trial (Lipomac Study, 2023)
A 24-subject randomized, crossover trial compared liposomal vitamin C (LVC) vs non-liposomal vitamin C (NLVC):
| Pharmacokinetic Parameter | LVC | NLVC | % Increase |
|---|---|---|---|
| Cmax (ng/mL) | 16,461.20 | 6,934.21 | +137% |
| AUC₀–t (mg·hr/dL) | 122,399.15 | 60,506.06 | +102% |
Conclusion: Liposomal Vitamin C is 2.02× more bioavailable.
Reference: Lipomac Study by Botanic Healthcare [2023]lipomac-flyer-clinical-…
Peer-Reviewed Research (Journal of Liposome Research, 2021)
“Liposomal vitamin C demonstrated 1.77× higher bioavailability than non-liposomal formulations.”
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Open-label, randomized human trial
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Enhanced encapsulation efficiency (65.85%)
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Particle size <100 nm for optimal permeability
Reference: Gopi & Balakrishnan, 2021 Evaluation and clinical…
WHY LIPOSOMES WIN: MULTIPLE ADVANTAGE LAYERS
| Feature | Benefit |
|---|---|
| Biocompatible lipid bilayers | Safe, non-toxic, easily recognized by human cells |
| Nano-sized vesicles (<200 nm) | Penetrate mucosal and epithelial barriers efficiently |
| Dual-phase encapsulation | Deliver both water-soluble and fat-soluble nutrients |
| Controlled release | Sustained absorption and higher plasma retention |
BEYOND VITAMIN C: WIDER IMPLICATIONS
Liposomal delivery has shown enhanced absorption in:
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CoQ10: Improved mitochondrial uptake for cellular energy
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Vitamin B12: Overcomes passive absorption limitations
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Glutathione: Protects antioxidant integrity during digestion
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Magnesium & Zinc: Facilitates uptake even in compromised GI conditions
These benefits are being explored for advanced formulations under The Absorbia Project™ pipeline.
TAP’S FORMULATION PHILOSOPHY
Every ingredient we use passes through a 3-step optimization process:
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Evaluate Biological Limitations
Understand where absorption bottlenecks occur. -
Apply Liposomal or Nano-Carriers
Match delivery technology to ingredient class. -
Validate with Human Data
Prioritize clinically backed formulations over theory.
TAP = Technology-Assisted Precision™
ABSORPTION IS THE FUTURE
Nutrient delivery must evolve from quantity on label to bioactive impact inside cells.
Liposomal Encapsulation Technology bridges that gap — and TAP is at the forefront of this shift.
