The Hidden Problem in Supplementation

Over 80% of nutrients in traditional capsules are lost before they ever reach your bloodstream.

Whether you're taking Vitamin C, B12, CoQ10, or curcumin — your body often absorbs only a small fraction of what's on the label. Why? Because most nutrients break down in the stomach, struggle through the gut wall, and are partially destroyed in the liver during what’s known as first-pass metabolism.

Solution? Change the delivery system.

That’s where Liposomal Encapsulation and Nano Delivery Systems come in — scientifically engineered to protect nutrients and enhance absorption at the cellular level.

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What is Liposomal Encapsulation?

Liposomal encapsulation involves enclosing nutrients within microscopic phospholipid vesicles (liposomes), which mimic the structure of cell membranes. This bio-mimetic structure enables enhanced solubility, protection against digestive enzymes, and direct cellular fusion for absorption.

Think of it like wrapping each nutrient in a microscopic bubble — shielding it from destruction and delivering it straight to where it's needed.

Key Benefits:

• Protects against stomach acid and enzymatic degradation

• Facilitates passive diffusion across intestinal membranes

• Allows nutrient delivery into cells via membrane fusion

• Reduces oxidative stress on the nutrient payload

Reference: Wu et al., Oral Delivery of Liposomes, Therapeutic Delivery, 2015Oral Delivery of Liposo….

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Nano Delivery — Going Smaller for Smarter Absorption

Nano delivery systems reduce nutrient size to the nanometer range (typically <200 nm), enabling faster, deeper absorption and bypassing common barriers like poor solubility or membrane impermeability.

Why it works:

• Nanoparticles offer greater surface area for absorption

• They can cross tight junctions in the intestinal wall

• Some are designed to bypass first-pass metabolism altogether

In essence: Smaller particles = faster, more complete absorption = better results.

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The Evidence – Human Clinical Trials

Vitamin C – Lipomac Human Trial

In a 12-participant, randomized crossover study, Lipomac™ Liposomal Vitamin C (500 mg) was shown to have 2.36x higher bioavailability than traditional ascorbic acid.

Citation: Botanic Healthcare, Lipomac Clinical Studylipomac-flyer-clinical-…

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The Mechanism in Action

Let’s break it down scientifically. Here’s what happens when a liposomal nutrient enters your system:

1. Mouth to Stomach
   – Liposome resists acidic pH (unlike naked vitamin molecules).

2. Intestinal Tract
   – Liposomes bind to intestinal cells or get taken up via M-cells in Peyer's patches.

3. Into the Bloodstream
   – Nutrients either diffuse through membranes or are absorbed intact by endocytosis.

4. Cellular Delivery
   – Liposomal shell fuses with cell membranes, releasing contents directly inside cells.

Conclusion: This results in enhanced bioavailability, longer plasma retention, and greater nutrient efficacy compared to traditional formulations.

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Addressing Stability and Safety

Critics of liposomal delivery often raise concerns about GI degradation or scale-up challenges. However, modern liposomal systems use:

• PEGylated coatings (e.g., polyethylene glycol) for gastric resistance

• Chitosan and polysaccharide polymers for mucoadhesion

• Solid-state delivery (freeze-dried or spray-dried) for improved shelf stability

These innovations have overcome many of the early limitations noted in oral delivery.

Citation: Wu et al., Oral Delivery of Liposomes, 2015Oral Delivery of Liposo…

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Why This Matters for TAP

At The Absorbia Project™, we believe efficacy should never be assumed — only measured.

That’s why we engineer all our supplements with cutting-edge nutrient delivery technologies, including liposomal encapsulation and nano carriers — backed by real data, not buzzwords.

• Every formula is designed for maximum absorption, not label inflation.

• We only use delivery technologies proven in human clinical trials.

• We apply clean-label, regulatory-safe ingredients — no unproven gimmicks.

Absorption Over Assumption™ is not just a slogan — it’s our standard.

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Scientific References:

1. Wu, W., Lu, Y., & Qi, J. (2015). Oral Delivery of Liposomes. Therapeutic Delivery, 6(11), 1239–1241. DOI:10.4155/tde.15.69 Oral Delivery of Liposo…

2. Botanic Healthcare Pvt. Ltd. Clinical Evaluation of Lipomac™ Liposomal Vitamin C, 2021. Internal Clinical Flyerlipomac-flyer-clinical-…

3. Shaw, T. K., et al. (2022). Research-based findings on scope of liposome-based cosmeceuticals: an updated review. Future Journal of Pharmaceutical Sciences, 8(46). DOI:10.1186/s43094-022-00435-3